abstract：:Cadmium ions applied to either (outer or inner) surface of the isolated toad skin dose-dependently increased the short-circuit current (SCC), the potential difference (V) and the active sodium conductance (G(Na)) in the concentration range 0.07-0.50mM. Maximal stimulatory effect was over 30% with an EC(50) of about 0....

journal_title：Journal of inorganic biochemistry

authors： Suwalsky M,Norris B,Cárdenas H

更新日期：2005-12-01 00:00:00

abstract：:A binuclear complex [(phen)Cu(mu-bipp)Cu(phen)](ClO(4))(4), where phen=1,10-phenanthroline and bipp=2,9-bis(2-imidazo[4,5-f][1,10]phenanthroline)-1,10-phenanthroline, has been synthesized and its interaction with calf-thymus DNA in the buffer containing 5mM Tris and 50mM NaCl has been studied by means of electronic ab...

journal_title：Journal of inorganic biochemistry

authors： Wu JZ,Yuan L,Wu JF

更新日期：2005-11-01 00:00:00

abstract：:A series of platinum(II) complexes with 2,9-disubstituted-6-benzylaminopurines has been prepared. The complexes have the following composition: cis-[Pt(Boh)(2)Cl(2)] (1), cis-[Pt(Oc)(2)Cl(2)] (2), cis-[Pt(Ros)(2)Cl(2)] (3), cis-[Pt(i-PrOc)(2)Cl(2)] (4), cis-[Pt(BohH(+))(2)Cl(2)]Cl(2) (5), cis-[Pt(OcH(+))(2)Cl(2)]Cl(2)...

journal_title：Journal of inorganic biochemistry

authors： Malon M,Trávnícek Z,Marek R,Strnad M

更新日期：2005-11-01 00:00:00

abstract：:To identify regulatory elements in the rat selenoprotein W (SeW) promoter, 2090, 1265, 741, and 404 base pair truncations of genomic DNA lying immediately upstream of the SeW coding sequence were cloned into a luciferase reporter vector (pGL3-Basic from Promega, Madison, WI, USA). 3656 and 406 base pair mouse SeW prom...

journal_title：Journal of inorganic biochemistry

authors： Hooven LA,Vorachek WR,Bauman AB,Butler JA,Ream LW,Whanger PD

更新日期：2005-10-01 00:00:00

abstract：:Polyamines are ubiquitous polycations that participate in cellular processes such as growth, differentiation and cell death. Among the different functions ascribed to these organic cations, the polyamine spermine is known to protect DNA from the damage produced by reactive oxygen species (ROS) generated by different a...

journal_title：Journal of inorganic biochemistry

authors： Pedreño E,López-Contreras AJ,Cremades A,Peñafiel R

更新日期：2005-10-01 00:00:00

abstract：:Rats were fed 100 microM aluminum maltolate for one year in their drinking water. Brain aluminum contents have increased 4.2-fold in the aluminum-treated group, whereas no significant changes in the body weight, brain weight, and brain protein content were observed. Long-term aluminum feeding induced apoptosis as asse...

journal_title：Journal of inorganic biochemistry

authors： Huh JW,Choi MM,Lee JH,Yang SJ,Kim MJ,Choi J,Lee KH,Lee JE,Cho SW

更新日期：2005-10-01 00:00:00

abstract：:Nanosized flower-like ZnO was synthesized by a simple hydrothermal method which is a convenient, environment friendly, inexpensive and efficient process. Raman spectroscopy, X-ray diffraction (XRD) and scanning electron microscope (SEM) were used to confirm the material structure and the crystallite microstructure. Th...

journal_title：Journal of inorganic biochemistry

authors： Liu YL,Yang YH,Yang HF,Liu ZM,Shen GL,Yu RQ

更新日期：2005-10-01 00:00:00

abstract：:Preparations of cis- and trans-platinum(II) complexes of diethyl (pyridin-4-ylmethyl)phosphate (4-pmOpe) have been described. These complexes were identified and characterized by far-IR, 1H NMR, 13C NMR, 31P NMR and 195Pt NMR and microanalyses. The crystal and molecular structure of trans-platinum(II) complex i.e., tr...

journal_title：Journal of inorganic biochemistry

authors： Kalinowska U,Matławska K,Checińska L,Domagała M,Kontek R,Osiecka R,Ochocki J

更新日期：2005-10-01 00:00:00

abstract：:The relationship between respiratory and neurological effects of exposure to aluminium (Al) was investigated in a group of foundry workers exposed to Al at concentrations below the threshold limit value (TLV) binding in Poland (2.0 mg Al2O3 m(-3)). Neurological and neurophysiological parameters indicated subclinical e...

journal_title：Journal of inorganic biochemistry

authors： Halatek T,Sinczuk-Walczak H,Rydzynski K

更新日期：2005-09-01 00:00:00

abstract：:Hydroxamate siderophores have been found to alleviate Al toxicity in bacteria. In Poaceae plants cyclic hydroxamates, like DIMBOA (2,4-dihydroxy-7-methoxy-1,4-benzoxazin-3-one) and its derivatives have mostly been studied in relation to either defence against insects or allelopathy. In this study the influence of Al o...

journal_title：Journal of inorganic biochemistry

authors： Poschenrieder C,Tolrà RP,Barceló J

更新日期：2005-09-01 00:00:00

abstract：:Aluminum, the most abundant neurotoxic metal in our biosphere, has been implicated in the etiology of several neurodegenerative disorders including Alzheimer's disease (AD). To further understand aluminum's influence on gene expression, we examined total messenger RNA levels in untransformed human neural cells exposed...

journal_title：Journal of inorganic biochemistry

authors： Lukiw WJ,Percy ME,Kruck TP

更新日期：2005-09-01 00:00:00

abstract：:Copper(II) complexes of three linear unsymmetrical tridentate ligands viz. N-methyl-N'-(pyrid-2-ylmethyl)ethylenediamine (L1), N,N-dimethyl-N'-(pyrid-2-ylmethyl)ethylenediamine (L2) and N,N-dimethyl-N'-((6-methyl)pyrid-2-ylmethyl)ethylenediamine (L3) have been isolated and characterized by elemental analysis, electron...

journal_title：Journal of inorganic biochemistry

authors： Raja A,Rajendiran V,Uma Maheswari P,Balamurugan R,Kilner CA,Halcrow MA,Palaniandavar M

更新日期：2005-08-01 00:00:00

abstract：:The syntheses, characteristics of dinuclear macrocyclic polyamine zinc complexes and their interaction with plasmid DNA are reported. The two cyclen (1,4,7,10-tetraazacyclododecane) moieties are bridged by rigid and flexible linkages. The crystal structures of Zn2C27H43N8O15Cl4 [5c.(ClO4)3.2H2O] and Zn2C30H43N10O13Cl3...

journal_title：Journal of inorganic biochemistry

authors： Xiang QX,Zhang J,Liu PY,Xia CQ,Zhou ZY,Xie RG,Yu XQ

更新日期：2005-08-01 00:00:00

abstract：:Nanosized polyphosphazene-platinum (II) conjugates with a wide range of molecular weight from 24,000 to 115,000 were synthesized to study their tumor selectivity by enhanced permeability and retention (EPR) effect and their antitumor activity. It has been found from biodistribution study that the present polyphosphaze...

journal_title：Journal of inorganic biochemistry

authors： Jun YJ,Kim JI,Jun MJ,Sohn YS

更新日期：2005-08-01 00:00:00

abstract：:Several metal ions and their complexes have been known to mimic the action of insulin in in vitro and in vivo systems. We prepared a family of Zn(II) complexes derived from amino ligands with Zn(Nn) (n=3 and 4) coordination modes, the insulinomimetic activity being estimated by an inhibitory effect of free fatty acid ...

journal_title：Journal of inorganic biochemistry

authors： Yoshikawa Y,Kondo M,Sakurai H,Kojima Y

更新日期：2005-07-01 00:00:00

abstract：:The strength of inhibition of beta-hematin (synthetic hemozoin or malaria pigment) formation by the quinoline antimalarial drugs chloroquine, amodiaquine, quinidine and quinine has been investigated as a function of incubation time. In the assay used, beta-hematin formation was brought about using 4.5M acetate, pH 4.5...

journal_title：Journal of inorganic biochemistry

authors： Egan TJ,Ncokazi KK

更新日期：2005-07-01 00:00:00

abstract：:A new bis(N-benzyl-benzotriazole)dichloro Co(II) complex (Co(bbt)(2)Cl(2)) was synthesized and the structure was characterized by X-ray crystallography, IR spectrum and elemental analysis. The electrochemical characterization of Co(bbt)(2)Cl(2) was measured in detail, and the interaction of this Co(II) complex with fi...

journal_title：Journal of inorganic biochemistry

authors： Jiao K,Wang QX,Sun W,Jian FF

更新日期：2005-06-01 00:00:00

abstract：:Selenium is an essential trace element for humans and other animals, and there is mounting evidence for the efficacy of certain forms of selenium as cancer-chemopreventive compounds. However, over the years, numerous elements such as As, Cu, Zn, Cd, Hg, Sn, Pb, Ni, Co, Sb, Bi, Ag, Au, and Mo have been found to inhibit...

journal_title：Journal of inorganic biochemistry

authors： Zeng H,Uthus EO,Combs GF Jr

更新日期：2005-06-01 00:00:00

abstract：:The reaction of Mycobacterium tuberculosis KatG and the mutant KatG(S315T) with two different organic peroxides is studied using resonance Raman spectroscopy. For the first time, an intermediate is observed in a catalase-peroxidase with vibrations that are characteristic of Compound II. The observation of this interme...

journal_title：Journal of inorganic biochemistry

authors： Kapetanaki SM,Chouchane S,Yu S,Magliozzo RS,Schelvis JP

更新日期：2005-06-01 00:00:00

abstract：:Samples of nano-MgO with varying particle sizes were prepared by four different methods using Mg(NO3)2.6H2O, Na2CO3, urea and ammonia as raw materials and characterized by X-ray diffraction (XRD), transmission electron microscopy (TEM), low temperature N2 adsorption-desorption measurements and FT-IR spectroscopy. Bact...

journal_title：Journal of inorganic biochemistry

authors： Huang L,Li DQ,Lin YJ,Wei M,Evans DG,Duan X

更新日期：2005-05-01 00:00:00

abstract：:A new Schiff base copper(II) complex, Cu(o-VANAHE)(2) (o-VANAHE = 2-(o-vanillinamino)-1-hydroxyethane), has been synthesized and characterized. Single crystal X-ray diffraction results suggest that this complex structure belongs to triclinic crystal system, space group P1 with the following crystallographic parameters...

journal_title：Journal of inorganic biochemistry

authors： Li LZ,Zhao C,Xu T,Ji HW,Yu YH,Guo GQ,Chao H

更新日期：2005-05-01 00:00:00

abstract：:Microperoxidase 8 (MP8) is able to react with alkyl- and aryl-isonitriles (RNC) both in its reduced and oxidized states, to form MP8Fe(II)- and MP8Fe(III)-CNR complexes. The coordination and spin states of these complexes have been fully characterized by UV-visible and resonance Raman spectroscopies. Both MP8Fe(II)- a...

journal_title：Journal of inorganic biochemistry

authors： Ricoux R,Lecomte S,Policar C,Boucher JL,Mahy JP

更新日期：2005-05-01 00:00:00

abstract：:The effect of pH on the X-band electron paramagnetic resonance (EPR) spectrum of ferrous nitrosylated human adult tetrameric hemoglobin (HbNO) as well as of ferrous nitrosylated monomeric alpha- and beta-chains has been investigated, at -163 degrees C. At pH 7.3, the X-band EPR spectrum of tetrameric HbNO and ferrous ...

journal_title：Journal of inorganic biochemistry

authors： Ascenzi P,Bocedi A,Fasano M,Gioia M,Marini S,Coletta M

更新日期：2005-05-01 00:00:00

abstract：:The biochemical characterization of individual nitrergic (NO releasing) neurons is a non-trivial task both in vertebrate and invertebrate preparations. In spite of numerous efforts, there are limited data related to intracellular concentrations of essential metabolites involved in NO synthesis and degradation. This si...

journal_title：Journal of inorganic biochemistry

authors： Moroz LL,Dahlgren RL,Boudko D,Sweedler JV,Lovell P

更新日期：2005-04-01 00:00:00

abstract：:Palladium(II) complexes of 2-benzoylpyridine thiosemicarbazone (H2Bz4DH) and its N4-methyl (H2Bz4M) and N4-phenyl (H2Bz4Ph) derivatives were obtained and fully characterized. [Pd(2Bz4DH)Cl] (1) crystallizes in the monoclinic space group P21/c with a=11.671(1), b=10.405(1), c=13.124(1), beta=115.60(1) degrees and Z=4; ...

journal_title：Journal of inorganic biochemistry

authors： Rebolledo AP,Vieites M,Gambino D,Piro OE,Castellano EE,Zani CL,Souza-Fagundes EM,Teixeira LR,Batista AA,Beraldo H

更新日期：2005-03-01 00:00:00

abstract：:Commercially available chromium supplements were tested for their DNA cleavage ability compared with synthetic chromium(III) complexes, including chromium(III) tris-picolinate [Cr(pic)3], basic chromium acetate [Cr3O(OAc)6]+, model complexes, and recently patented Cr-complexes for use in supplements or therapy. Four d...

journal_title：Journal of inorganic biochemistry

authors： Chaudhary S,Pinkston J,Rabile MM,Van Horn JD

更新日期：2005-03-01 00:00:00

abstract：:A zinc(II) complex having planar tridentate ligand, bzimpy, where bzimpy is 2,6-bis(benzimidazol-2-yl) pyridine was synthesized and characterized by UV, NMR, infrared spectroscopy and fluorescence spectra. The zinc complex acts as dibasic acids, in which N-H protons on benzimidazole moieties are responsible for a depr...

journal_title：Journal of inorganic biochemistry

authors： Wang J,Shuai L,Xiao X,Zeng Y,Li Z,Matsumura-Inoue T

更新日期：2005-03-01 00:00:00

abstract：:In this study emission and synchronous-scan fluorescence spectroscopy have been used to investigate the interaction of the class A (oxygen seeking 'hard acid') metal Al(3+), with Suwannee River fulvic acid (SRFA), as well as competition between Al(3+) and several other metal ions (Ca(2+), Mg(2+), Cu(2+), Pd(2+), La(3+...

journal_title：Journal of inorganic biochemistry

authors： Zhao J,Nelson DJ

更新日期：2005-02-01 00:00:00

abstract：:Theoretical and spectroscopic studies of 3,3'-benzylidenedi-4-hydroxycoumarin (bhc) have been performed. B3LYP/6-31G* calculations reproduced the experimental molecular structure of bhc and showed two O-H...O asymmetrical intramolecular hydrogen bonds with O...O distances 2.638 and 2.696 A. The calculated Fukui functi...

journal_title：Journal of inorganic biochemistry

authors： Kostova I,Trendafilova N,Momekov G

更新日期：2005-02-01 00:00:00

abstract：:The non-covalent interaction of the complexes [Pt(bpy)(R,R'NCSNR'',R''')(2)]Cl(2) (bpy=2,2'-bipyridine; R=R'=R''=R'''=H; R=Me, R'=R''=R'''=H; R=n-Bu, R'=R''=R'''=H; R=p-tolyl, R'=R''=R'''=H; R=Et, R'=H, R''=Et, R'''=H) with calf thymus DNA has been studied at pH 7 and 25 degrees C. The processes give rise to: (i) reve...

journal_title：Journal of inorganic biochemistry

authors： Cusumano M,Di Pietro ML,Giannetto A,Vainiglia PA

更新日期：2005-02-01 00:00:00

abstract：:Four imidazolate-bridged binuclear copper(II)-copper(II) and copper(II)-zinc(II) complexes viz., [(Bipy)(2)Cu-Im-Cu(Bipy)(2)](ClO(4))(3).CH(3)OH, [(Phen)(2)Cu-Im-Cu(Phen)(2)](BF(4))(3).2CH(3)OH, [(Bipy)(2)Cu-Im-Zn(Bipy)(2)](BF(4))(3), and [(Phen)(2)Cu-Im-Zn(Phen)(2)](BF(4))(3), (Bipy=2,2'-Bipyridyl, Phen=1-10-Phenanth...

journal_title：Journal of inorganic biochemistry

authors： Patel RN,Singh N,Shukla KK,Gundla VL,Chauhan UK

更新日期：2005-02-01 00:00:00

abstract：:We have studied the ground state of a realistic model of oxyheme with multiconfigurational second-order perturbation theory (CASPT2). Our results show that the ground-state electronic structure is strongly multiconfigurational in character. Thus, the wavefunction is a mixture of many different configurations, of which...

journal_title：Journal of inorganic biochemistry

authors： Jensen KP,Roos BO,Ryde U

更新日期：2005-01-01 00:00:00

abstract：:The coordination chemistry of the one-electron reduced form of nitric oxide, termed a nitroxyl or nitrosyl hydride (NO- or HNO), is described with special focus on its interaction with hemes and heme model complexes. Nitroxyl intermediates have been proposed in the catalytic cycles of several heme-based nitrite and ni...

journal_title：Journal of inorganic biochemistry

authors： Farmer PJ,Sulc F

更新日期：2005-01-01 00:00:00

abstract：:We present hereby an overview of the reactions of cytochrome c oxidase, the terminal enzyme of the mitochondrial respiratory chain, with ligands (primarily oxygen) and electrons, pointing out where necessary unresolved facts or questionable interpretations. ...

journal_title：Journal of inorganic biochemistry

authors： Brunori M,Giuffrè A,Sarti P

更新日期：2005-01-01 00:00:00

abstract：:The new cyclic tetrapeptide c(HGHK) was synthesised in the solid phase and its complexes with copper(II) were studied in aqueous solution at various pH values by means of potentiometric and spectroscopic methods (UV, EPR, CD). Six mononuclear coordination species were clearly identified within the pH range 3-11. Spect...

journal_title：Journal of inorganic biochemistry

authors： Brasun J,Gabbiani C,Ginanneschi M,Messori L,Orfei M,Swiatek-Kozlowska J

更新日期：2004-12-01 00:00:00

abstract：:The reactions of hydroquinone with hydrogen peroxide catalyzed by transition metal ions Cu2+, Fe2+, Fe3+, Co2+ and Mn2+ were investigated in aqueous solution at 25 degrees C. Two copper (II) complexes (bis(dimethylglyoxime) copper(II) and 5,7,7,12,14,14-hexamethyl-1,4,8,11-tetraazacyclotetradeca-4,11-dienatocopper(II)...

journal_title：Journal of inorganic biochemistry

authors： Meng XG,Guo Y,Hu CW,Zeng XC

更新日期：2004-12-01 00:00:00

abstract：:The activity against human cancer cell lines including ovarian: A2780, A2780(cisR), cell up take, DNA-binding and nature of interaction with pBR322 plasmid DNA have been studied for four multinuclear complexes code named DH4Cl, DH5Cl, DH6Cl and DH7Cl, having the general formula: [[trans-PtCl(NH(3))(2)](2)mu-[trans-Pd(...

journal_title：Journal of inorganic biochemistry

authors： Daghriri H,Huq F,Beale P

更新日期：2004-11-01 00:00:00

abstract：:The rates at which phosphonocarboxylate and diphosphonate ligands remove iron from the serum iron transport protein transferrin at 25 degrees C and pH 7.4 have been evaluated. These ligands show a combination of saturation and first-order kinetics with respect to the free ligand concentrations. The ability of the liga...

journal_title：Journal of inorganic biochemistry

authors： Harris WR,Brook CE,Spilling CD,Elleppan S,Peng W,Xin M,Wyk JV

更新日期：2004-11-01 00:00:00

abstract：:The pH- and time-dependent reactions of the anticancer drug cisplatin, cis-[PtCl(2)(NH(3))(2)], with the peptides Ac-Gly-Met-Gly-OH, Ac-Ser-Met-OH and Ac-Met-His-OH (Gly=glycyl, Met=methionyl, Ser=seryl, His=histidyl) at 313 K have been investigated by high-performance liquid chromatography, nuclear magnetic resonance...

journal_title：Journal of inorganic biochemistry

authors： Manka S,Becker F,Hohage O,Sheldrick WS

更新日期：2004-11-01 00:00:00

abstract：:The novel anticancer drug ([[trans-PtCl(NH(3))(2)](2)-mu-[trans-Pt(NH(3))(2)(NH(2)(CH(2))(6)NH(2))(2)]](NO(3))(4)) (BBR3464, 1,0,1/t,t,t, TPC) forms a 1,4-interstrand cross-linked adduct with the self-complementary DNA octamer 5'-d(ATG*TACAT)(2)-3', with the two platinum atoms coordinated in the major groove at N7 pos...

journal_title：Journal of inorganic biochemistry

authors： Qu Y,Scarsdale NJ,Tran MC,Farrell N

更新日期：2004-10-01 00:00:00